TPJ Author Information

 Before submitting a manuscript to The Permanente Journal, please review our About the Journal page as well as our Manuscript Preparation Instructions.


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checklist is also available to facilitate manuscript preparation.

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Original Research Articles

Present scientific research reports of original, empirically based research—with results and analysis—of great clinical importance. These include: Randomized trials, intervention studies, outcomes research, case-control studies, observational studies, highly significant surveys, advanced quality improvement studies (guidelines and resources for quality improvement articles are available from SQUIRE at:, and rigorous evaluations of clinical best practices in large populations. Limit of 5000 words, 5 tables, 5 figures; structured abstract required.

Review Articles

Collect relevant, evidence-based reviews of clinical practice topics written for the general physician, though articles on specialty practice are encouraged to inform both generalists and specialists. These articles should include the most important recent references in the field. Limit of 5000 words, up to 40 references; abstract required.

Case Reports

Collect data from the point of care integrating clinical expertise with external evidence to inform the clinical practice guidelines and the delivery of high-quality individualized healthcare. “Good case reporting demands a clear focus, to make explicit to the audience why a particular observation is important in the context of existing knowledge” (Vandenbroucke 2001). The CARE guidelines for case reports help authors reduce bias, increase transparency, and provide early signals of what works, for which patients, and under which circumstances and are also available from the EQUATOR Network. Whenever appropriate, please follow the CARE guidelines checklist. Limit of 2500 words, 3 tables or figures. Abstract and timeline are required.

CARE references:

1.    Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley DS. The CARE guidelines: consensus-based clinical case reporting guideline development. JClinEpi 2014 Jan;46e51.

2.     Riley DS, Barber MS, Kienle GS, Aronson JK, von Schoen-Angerer T, et al. CARE 2013 Explanation and Elaborations: Reporting Guidelines for Case Reports. JClinEpi 2017 Sep;89:218-235. doi: 10.1016/jclinepi.2017.04.026.


Present a point of view of general interest about a currently relevant topic; comment on a published article touching on an important subject; highlight a significant contribution that has the potential to change the field; or to discuss a debate or conflicting data or findings. Limit of 2000 words with no more than 20 references. No abstract is required.

Letters to the Editor

Authors are invited to present opinions in response to articles already published in TPJ. Letters to the Editor should comment on a subject of importance and interest to the broader readership. The Letter may be sent to the author(s) of the originally published article and possibly to other interested parties for a response to be published in the journal as part of the Letter. Please note that the journal will not consider Letters to the Editor regarding content that was published more than 3 months prior. Correspondence concerning articles that have not been published in TPJ will not be considered. Limit of 500 words and a maximum of 5 references, the first of which must be the citation for the original article under discussion. Letters may contain figures or tables only if they show data that refute the conclusions of the originating article. Figures or tables showing unpublished data in support of the conclusions of the originating article will not be considered. No abstract is required.


Editorials are generally written by or solicited by the Editor-in-Chief and are related to an article published in TPJ. Limit of 1000 words with no more than 10 references. No abstract is required.



Authors submitting a manuscript to the journal do so with the understanding that if it is accepted for publication, copyright of the article, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the publisher. The publisher will grant any reasonable request by the author for permission to reproduce any part of his/her contribution to TPJ.

Authors should consider the following and include required statements, forms, or information with their submission as applicable:

  • IRB Approval – Any manuscript that has been submitted for institutional review board approval, whether given or deemed unnecessary, must include a copy of the IRB letter. Documentation of IRB approval or exemption must be appended to the manuscript being submitted for publication in TPJ. If there has been no IRB review of the project, please indicate such on the title page of the manuscript. In this case, the article will be reviewed to determine if IRB review should have been conducted. The result of this review may determine whether or not the manuscript will be considered for publication.
  • Informed Consent – Authors must attest to having written informed consent from the case patient and/or case patient’s legal proxy for any manuscript that includes identifiable patient information (e.g. Case Reports). Do not upload a signed copy of informed consent forms to the ScholarOne Manuscripts website for The Permanente Journal. Any informed consent forms that are uploaded will be deleted. Authors may be asked to furnish a BLANK copy of their institution’s informed consent form. All authors are assumed to be in compliance with their home institution’s policies for storage and retention of informed consent form.
  • Photo Release – Any manuscript that includes photographs of individuals who are identifiable, must include a photo release signed by those individuals.
  • Reprint Permission – Authors must obtain permission to reprint any material taken from another source (Tables or Figures from another journal or website, for example).
  • Manuscripts published by TPJ are in accordance with the International Committee of Medical Journal Editors (ICJME) Uniform Requirements (2019 Update). Authors seeking more information on appropriate manuscript preparation may review these requirements at:



All submissions to TPJ must include a cover letter indicating that the manuscript has not been published or simultaneously submitted for publication in whole or in part elsewhere, except for a scientific abstract, unless otherwise specified. If applicable, the letter must include a full statement to the editor about all submissions and previous reports (including meeting presentations and posting of results in registries) that might be regarded as redundant or duplicate publication of the same or very similar work. The author must also alert the editor in the cover letter if the manuscript includes subjects about which the authors have published a previous report or have submitted a related report to another publication. Appropriate reference information and copies of such material must be included as well. The title of the manuscript should indicate that it is a secondary publication.

Although individual sharing of content is permitted, reprint permission is required for republishing or reprinting journal content. See Reprint Permission information.

TPJ is strongly committed to ethical publication practices and is strongly committed to avoiding plagiarism, duplicate publication, research misconduct, and breaches of confidentiality. Before a manuscript is sent for peer review, it is processed through Crossref, a text-matching software service. Because images are frequently of concern with regard to plagiarism or misconduct, authors should disclose any manipulation of submitted images. Please review our Ethics Statement.

Authors are expected to promote their own work. Authors may share a link to published content with colleagues, family, and friends; they are encouraged to promote their work on social media (Facebook, Twitter, Instagram, etc).


Manuscripts will be assigned to an editor for review. The editor will make an initial decision to send the manuscript to peer reviewers or to reject the manuscript. Authors are given the opportunity to note anyone they prefer NOT to review their submission and should supply a list of experts in the field who would be potentially appropriate to review the article. Editorial decisions, before or after peer review, are based on editorial priorities, manuscript quality, reviewer recommendations, relevance, quality of work described, and applicability to daily clinical practice. Decisions will be to provisionally accept the manuscript, to request a revised manuscript, or to reject the manuscript. Reviewer comments will be conveyed to the author at the discretion of the editor with a request to address any issues raised by the reviewers.


If the article is accepted for publication, editorial revision (copyediting) may be made to aid clarity and understanding without altering meaning. Authors will be given the opportunity to review a PDF proof of the article once it has gone through the copyediting and design process. Authors are asked to review the proofs for typesetting or copyediting errors (accidental changes in meaning). Proofs must be returned within 48 hours. If you anticipate being away, it is your responsibility to contact the Editorial Office to request an extension. Authors are reminded that they assume full responsibility for final wording and for the form of all materials approved for publication.


Methods and Statistics

Statistical methods should be described with enough detail to enable a knowledgeable reader with access to the original data to reproduce the reported results. When possible, quantify findings and present them with appropriate indicators of measurement error or uncertainty (eg, confidence intervals). Avoid relying solely on statistical hypothesis testing, such as the use of p values, which fails to convey important quantitative information. Give details about randomization. Describe the methods for and success of any blinding observations. Report losses to observation (such as dropouts from a clinical trial). For multivariate models, report all variables included in models, and report model diagnostics and proportion of variance explained by both individual variables and the complete model.

Put a general description of methods in the Methods section. Restrict Tables and Figures to those needed to explain the argument of the manuscript and to assess its support. Use graphs as an alternative to Tables with many entries; do not duplicate data in graphs and Tables. Avoid nontechnical terms in statistics, such as significant (which should only be used in terms of statistical significance), random (which implies a randomizing device), normal, correlations, and sample. Define statistical terms, abbreviations, and most symbols.

Conduct and Research Design

To address issues related to design and conduct of research, please review the EQUATOR Network guidelines, including CONSORT, STROBE, and PRISMA.

For more information in writing and preparing quality-improvement articles, please review the guidelines and access the resources available from SQUIRE at:

Additional Resources

1.    Lang TA, Altman DG. Basic statistical reporting for articles published in biomedical journals: the "Statistical Analyses and Methods in Published Literature" or "The SAMPL Guidelines." In: Smart P, Maisonneuve H, Polderman A (eds). Science Editors’ Handbook, European Association of Science Editors, 2013.

2.    Lang TA, Secic M. How to report statistics in medicine. 2nd ed. Philadelphia, PA: American College of Physicians; 2006.


Corrections or errata will be published in a subsequent issue of the journal with the original article appropriately cited. The electronic version of the article will be corrected and will appear online in its corrected form.

TPJ will work to correct errors as they occur. Content that has been indexed is considered the final published record and must be preserved; therefore, all changes to articles must be made as a formal correction. Corrections will be published online and will be linked to the original article. Corrections will be picked up by indexing services and other aggregating databases.

Corrections will be reviewed and considered if they affect the publication record, the scientific integrity of the paper, or the reputation of the authors or of the journal. Corrections that do not significantly affect the paper may not be approved (i.e. a punctuation or spelling error).

Retractions will be considered if results are invalid or ethical guidelines have been violated (i.e. applicable cases of plagiarism or ghostwriting). All authors will be asked to sign a retraction detailing the error and how the conclusions were affected. Retractions will be published online and will be linked to the original article and will be picked up by indexing services and other aggregating databases.

All decisions about corrections or retractions are made by the Editor. Author consultation may be required. In situations where coauthors disagree about a correction, the Editors will consult with independent peer-reviewers before applying the appropriate correction. The dissenting author(s) position will be noted on the correction.

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Author Resources

ICMJE – Recommendations for conduct and reporting of scholarly work are available from ICMJE at:

SQUIRE - Guidelines and resources for quality-improvement articles are available from SQUIRE at:

CONSORT – Guidelines and resources for reporting of randomized controlled trials are available from:

CARE Guidelines – Guidelines and resources for reporting case reports are available from:


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